Ulcerative Colitis

University of Minnesota
Trials underway

A placebo-controlled trial at the University of Minnesota investigating the role of bacteria linked to hydrogen sulfide gas and inflammation in Ulcerative Colitis. Visit their site to learn more about the study. Hear more from the principal investigator, Dr. Byron Vaughn and in their published journal article.

University of Minnesota
Completed Trials

Investigators studied the connection between high levels of Hydrogen sulfide, sulfate reducing bacteria and inflammation in Ulcerative Colitis patients. The study suggests that "the increasing severity of inflammation in Ulcerative Colitis is due to the dilution of beneficial factors, concentration of toxic factors and changing detoxification capacity of the host, all of which are intimately linked to the nutrient flow from the diet." Read the full literature review here.

University of Minnesota
Completed Trials
  • Researchers studied the impact of diet on intestinal Sulfate Reducing Bacteria. This pilot crossover study monitored the gut bacteria of four healthy individuals, who followed two interventional diets for 10-14 days, containing high or low sulfur-containing amino acids (SAA). No major changes occurred in the quantity of Sulfate Reducing Bacteria, suggesting that "dietary interventions alone may be insufficient for rapid therapeutic targeting of Sulfate Reducing Bacteria." Read the trial publication here.