Complications of Intensive Chemotherapy for Acute Leukemia

A randomized, double-blind, placebo controlled trial investigating the impact of microbial restoration on patients being treated with intensive chemotherapy for acute leukemia. Study details are available here. Initial findings indicate Microbiota Transplant Therapy is safe in this patient population. A phase 2, randomized, double-blind trial found the patients receiving the active MTT therapy had a lower rate of infection than the placebo group.

Researchers are preparing for a third clinical trial to investigate whether FMT after an allogenic stem cell transplant, when compared to placebo, can prevent Acute-Versus-Host disease.